Maya

http://health.nytimes.com/health/guides/disease/sickle-cell-anemia/overview.html http://www.cdc.gov/ncbddd/sicklecell/data.html Frey, Rebecca j. U.X.L Encyclopedia of diseases and disorders.Farmington Hills : Gale Cengage Learning, 2009.Print.

=//**Sickle Cell Anemia**//= //**__What is sickle cell anemia__**//
 * **Sickle cell anemia is an autosomal disorder when** //**the body makes red blood cells that are shaped like a crescent** **instead of doughnut like which cause less oxygen to be able to spread around the body and other problems**//

//**__What causes sickle cell anemia and other factors__**// >
 * **It is an inherited disorder that is cause by a mutation in the hemoglobin-beta gene on chromosome 11. __//Hemoglobin//__ is a protein found in red-blood cells that carries oxygen from the lungs to other parts of the body** . **//Even though the 11th chromosome is affected people with this disorder still have 46 chromosomes//**.
 * **//Race is a major factor if your ancestors originated from South and Central America, the Caribbean, Middle East, Africa , Southeast Asia , then you are more likely to have sickle cell anemia or carry the trait//**
 * //__Symptoms of Sickle cell anemia__//**
 * **//Attacks of abdominal pain//****//Fatigue [[image:mccarthyscoolscience/cells.jpg align="right"]][[image:mccarthyscoolscience/be.jpg align="right"]]//**
 * **//Bone pain//**
 * //**Fever**//
 * //**Yellowing of the eyes**//
 * **//Breathlessness//**
 * **//Delay in puberty and growth//**

//**__L__**__**ife Expectancy and Statistics**__//
 * **//people with homozygous sickle cell disease (HbSS) have life expectancy in the mid-40s.But with early diagnosis and management, the life expectancy in sickle cell is increasing.//**
 * **//1 in 10 African-Americans have sickle cell trait//**
 * **//1 in 100 Hispanic Americans have sickle cell trait.//**
 * **//Life expectancy can range from age 42 to age 68 depending on how severe the person's anemia is//**
 * //**affects 90,000 to 100,000 Americans each year**//
 * //**occurs among about 1 out of every 500 Black or African-American births.**//

__//**Fun facts**//__
 * //**Geneticist say the sickle cell anemia originated in 5 different parts of Africa, including Saudi Arabia**//
 * **//The sickle cell gene is more resistant that the one type of malaria, which helped it spread//**
 * **//Sickle cell is the most common inherited blood disorder in North America//**
 * **//To get sickle cell you must inherit the defective gene from both parents//**