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‍__** Downs Syndrome **__ Downs Syndrome is an autosomal disodercaused by a mutation of the 21st chromosome. Each cell in the body has three copies of the 21st chromosome, instead of the usual two copies.
 * What is Downs Syndrome?**

‍ Mosiac Downs Syndrome: Only some of the cells have an extra copy of the 21st chromosome. Translocation Downs Syndrome: Part of the 21st chromosome becomes attached (translocated) to another chromosome during the formation of reproductive cells, usually the 14th or 15th chromosome.
 * Types of Downs Syndrome**

**Characteristics/Symptoms of Downs Syndrome**
 * 1) Short stature (grow slow, shorter as an adult)
 * Weak muscles (Hypotonia). Weak abdominal muscles make the stomach stick out.
 * Short, wide neck with excess fat and skin.
 * Short, stocky arms and legs.
 * Wide space between the big and 2nd toe.
 * Single crease across palms. (Transverse palmar crease/Simian line)
 * Small, low set ears.
 * Irregular shaped mouth and tounge.
 * Nasal bridge that looks pushed in.
 * Tissue buildup on the iris of the eye (Brushfield's Spots), doesn't affect vision.
 * Irregular shaped teeth that come in late or not normal sequence.
 * Intellectual disability.
 * Heart deffects.
 * Mental retardation. (Adults may have an age level of a 3-7 year old.)
 * Epicanthic folds on eyes. (fold of skin over the inner corner of the eye.)

**Life Expectancy** Today, children with Downs Syndrome can expect to live to their 50's. Although, 85% of fetuses spontaneously abort, or die in the womb. 55% of Downs Syndrom South American babies die within their first year of life. By 35 years of age, 25% begin to develop Alzheimer Syndrome. On average, 1 in 800 Births of Downs Syndrome children are born. The risks of this go up as you get older.

**Extra Facts**
 * Women who have already had a Downs Syndrome child are at a higher risk of another Downs Syndrome child.
 * Women with Downs Syndrome have a 1/2 chance of having their children with Downs Syndrome.
 * Many affected fetuses are lost in miscarriages.
 * This Syndrome is inherited.

No outside Risk factors.
 * Risk Factors**
 * advancing maternal age.
 * having a previous child with Downs Syndrome.
 * being a carrier for the genetic translocation for Downs Syndrome.


 * Refrences**

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