Patrick

=__**Maple syrup urine disease (MSUD)**__=

__**What is it?**__
Maple syrup urine disease is an autosomal, metabolic disorder where the body cannot break down certain parts of protiens properly. It can make the affected person's urine smell like maple syrup, hence the name. This disease is hereditary.

**__What causes MSUD?__**
Maple syrup urine disease is caused by a genetic defect in which there is a mutation in chromosome 19 where there is a depletion of genes used to break down amino acids, so if there is a mutation the amino acids will not be broken down properly and may lead to a dangerously high level of amino acids which can cause MSUD.

__**Symptoms of MSUD**__
Avoiding food Coma Feeding difficulties seizures vomiting

Urine that smells like maple syrup(obviously)

**__Statistics__**
Only 1 out of every 180,000 babies is born with MSUD In some areas with a higher carrier rate the chances can be as low as 1 in 385

**__Extra facts__**
If MSUD is left untreated it can result in brain damage and eventully death. The person's urine is not actual maple syrup. It just smells like it. Affected persons can lead a healthy life with some dietary restrictions.